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National Institute of Health News

African American children may need different asthma treatments

NIH Recherche Médicale - mar, 15/10/2019 - 00:00
Results from a study of African American children with poorly controlled asthma contrast with those seen in other populations in previous studies. The findings highlight the importance of including people of diverse ages and races.

Gut microbes affect harmful compound in red meat

NIH Recherche Médicale - mar, 15/10/2019 - 00:00
Researchers identified an enzyme in gut bacteria that releases an inflammation-causing carbohydrate from meat. The findings suggest strategies to reduce the risk of certain diseases associated with eating red meat.

ALS-related mutations prevent RNA transport in nerves

NIH Recherche Médicale - mar, 15/10/2019 - 00:00
Researchers discovered that ALS-related mutations prevent RNA transport from the nucleus to other areas of nerve cells. The results suggest an avenue to investigate new treatments for diseases linked to problems with this process.

REM sleep may help the brain forget

NIH Recherche Médicale - mar, 01/10/2019 - 00:00
Scientists identified neurons in mice that are involved in actively forgetting memories during dream sleep.

How cancer vesicles breach the blood-brain barrier

NIH Recherche Médicale - mar, 01/10/2019 - 00:00
Small particles from cancer cells called extracellular vesicles cross the blood-brain barrier to make the brain more hospitable to metastatic tumors.

Disrupting host protein blocks enterovirus infections in mice

NIH Recherche Médicale - mar, 01/10/2019 - 00:00
Researchers found a host protein that enteroviruses, which cause many cases of the common cold as well as more serious diseases, need to replicate.

Two commonly used drugs for uveitis perform equally well

NIH Recherche Médicale - mar, 24/09/2019 - 00:00
The drug methotrexate performed as well as the more expensive mycophenolate mofetil for treating uveitis, a form of eye inflammation. The findings provide new guidance for treatment.

Peanut allergy protection limited after oral immunotherapy

NIH Recherche Médicale - mar, 24/09/2019 - 00:00
After people with peanut allergy received oral immunotherapy to induce tolerance to peanut, most who discontinued or had a reduced dose lost the therapy’s protective effects.

Extending preservation time for donated livers

NIH Recherche Médicale - mar, 24/09/2019 - 00:00
A new preservation method protected human livers during cooling and kept them healthy for more than 24 hours.

Emergency department closures impact treatment quality nearby

NIH Recherche Médicale - mar, 17/09/2019 - 00:00
When emergency departments closed, people treated for a heart attack at nearby crowded hospitals had worse outcomes.

Gene identified in people who need little sleep

NIH Recherche Médicale - mar, 17/09/2019 - 00:00
Scientists identified a gene that causes people to naturally sleep less than six and a half hours each night without any apparent ill effects.

Enzyme active in cancer also protects normal cells

NIH Recherche Médicale - mar, 17/09/2019 - 00:00
Researchers found that the enzyme telomerase, which is active in most tumor cells, may also protect healthy adult cells from becoming cancerous.

Air pollution associated with worsening emphysema

NIH Recherche Médicale - mar, 10/09/2019 - 00:00
Common air pollutants were associated with increases in emphysema over a decade of follow-up. The results may help explain why some people who never smoked develop emphysema.

How brown fat improves metabolism

NIH Recherche Médicale - mar, 10/09/2019 - 00:00
Researchers gained key insights into brown fat’s effects on the body’s metabolism. The findings reveal targets for developing new treatments for obesity and diabetes.

Brain cells underlying stuttering identified in mice

NIH Recherche Médicale - mar, 10/09/2019 - 00:00
Gene mutations related to human stuttering also caused vocalization defects and a loss of brain cells called astrocytes in mice. The findings reveal insight into the neurological mechanisms.

Enterovirus infection linked to acute flaccid myelitis

NIH Recherche Médicale - mar, 27/08/2019 - 00:00
Evidence of infection with an enterovirus was found in about 80% of people with the rare but serious condition called acute flaccid myelitis.

Brain scans reveal marker for severe MS

NIH Recherche Médicale - mar, 27/08/2019 - 00:00
Researchers found that dark rimmed spots on the brain may be a hallmark of more aggressive and disabling forms of multiple sclerosis. The findings suggest an avenue to explore for new disease treatments.

High-sugar intake worsens autoimmune disease in mice

NIH Recherche Médicale - mar, 27/08/2019 - 00:00
In mouse models of autoimmune disorders, drinking sugary water worsened disease by activating inflammatory immune cells. The findings suggest a low-sugar diet may help prevent or treat autoimmune diseases.

Aspirin use may be widespread despite new guidelines

NIH Recherche Médicale - mar, 13/08/2019 - 00:00
A study suggests that millions of U.S. adults may take a daily aspirin for cardiovascular disease prevention without any clear benefit.

Compound reduces chronic itch in mice

NIH Recherche Médicale - mar, 13/08/2019 - 00:00
Researchers identified a compound that can reduce itch in mice by blocking a receptor in the spinal cord. Future studies could lead to a drug for testing in people.

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